A DIFFERENCE SCHEME FOR SOLVING THE EQUATIONS OF TUMOR GROWTH SUBJECT TO THE RESTRICTED FLOW OF MOTILE CELLS
DOI:
https://doi.org/10.14529/mmp170208Keywords:
substrate taxis, the problem with movable boundary, break allocationAbstract
The article investigates one-dimensional mathematical model of tumor growth represented by a system of quasi-linear parabolic equations. We assume certain restrictions on the full ow of the motile tumor cells, leading to the possible degeneration of the system into a hyperbolic type and emergence of discontinuous (weak) solution. To nd weak solution we consider tumor growth as the emergence of a new phase. Thus we have a generalized (nonlinear) Stefan problem. The authors propose and implement a dierence scheme with the explicit statement of the phase-change moving boundary to solve the problem. It is shown that this approach allows to describe dierent regimes of tumor growthReferences
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