PROBIOTIC PRODUCT BASED ON BIFIDO-, LACTOBACILLI AND PEPTIDE ULTRALYSATES

Abstract

Priorities in biotechnology and nutritionology are considered. Special attention is paid to the development of specialized probiotic products aimed at shaping the microbiome and ensuring the quality of life. A probiotic product has been developed in the form of dietary supple-ments based on probiotics: bifido (Bifidobacterium bifidu, Bifidobacterium infantis, Bifidobacterium longum, Bifidobacterium breve), lactobacilli (Lactobacillus casei, Lactobacillus rhamnosus, Lactobacillus acidophilus) and peptide ultralysates (Propionibacterium freudenreichii, Propionibacterium arabinosum). The following prebiotics are used: lactulose, beta-glucan and fibrigam. The formulation also includes vitamins B1 (thiamine,) and B6 (pyridoxine), which are coenzymes in enzymes and are necessary for the normal growth and development of bacteria in the human intestine. The formulation of the biocomplex in the form of dietary supplements is scientifically substantiated, and the characteristics of biologically active ingredients are given. Regulated quality indicators of the developed biocomplex have been established: organoleptic – white to cream powder, inclusions, specific smell and taste are acceptable; the content of beta-glucans, mg, in 1 capsule is from 12 to 18. Sanitary and hygienic and sanitary and toxicological safety indicators were studied after 16 months of manufacturing the product at a temperature of 2 to 6 °C and a relative humidity of no more than 60 %, which made it possible to determine the storage time and conditions – 1 year under the above conditions. The developed probiotic biocomplex is recommended as a tonic and preventive agent for maintaining the normal flora of the small and large intestines, preventing intestinal infections, normalizing digestion and forming healthy immunity. The active ingredients of the specialized product have synergistic properties and form its probiotic orientation.