METHODOLOGICAL APPROACHES TO CREATION OF ENRICHED FOOD PRODUCTS WITH PROVEN EFFICIENC
Keywords:
methodology, biologically active substances, enriched food products, proven efficiency.Abstract
The work suggests a methodology for obtaining healthy diet food products with proven effectiveness. In recent years, the production of food products enriched with biologically active substances is one of the most popular areas in various fields of the food industry. At the same time, there is a necessity to confirm the declared beneficial effects of food product enrichment. The organization of clinical research, as a rule, is associated with significant financial, time and labour costs. In this connection, there appears a necessity to develop an adequate pre-clinical research algorithm for the effectiveness of food products enriched with biologically active substances. Development of a food matrix and development of systems for biologically active substances delivery, such as microemulsions, liposomes, microgels, nano-emulsions, conjugates, microclusters, and others, take a special place in the confirmation of an enriched food product effectiveness. In spite of the array of data related to the study of various delivery systems, the problems of determining the mechanisms of chemical transformations when embedding encapsulated biologically active substances in the food matrix, their translation into the cellular systems of the human body, and participation in metabolic processes remain unsolved. The abovementioned should be taken into account when assessing the enriched food product effectiveness. It is equally important to analyze the consumer perception of enriched food, assess the technological accessibility of their production, the sufficiency of resource provision. On the basis of scientific literature analysis, there is taken an attempt to formulate a methodology for the development of the product, enriched with biologically active substances, with proven effectiveness, which grounds on a comprehensive, interdisciplinary approach to the organization of pre-clinical studies, including in vitro, in silico, and in vivo methods.
References
Борисенко, А.А. Проектирование сбалансированных поликомпонентных пищевых продуктов на основе их нутриентного состава / А.А. Борисенко, Г.И. Касьянов, А.А. Борисенко (мл.), А.А. Запорожский // Известия вузов. Пищевая технология. – 2005. – № 2-3. – С. 106–107.
Липатов, Н.Н. Методологические подходы к проектированию рецептур многокомпонентных пищевых продуктов III поколения / Н.Н. Липатов // Разработка процессов получения комбинированных продуктов питания: материалы Всес. научно-техн. конф. – М., 1988. – С. 10–11.
Липатов, Н.Н. Методология проектирования продуктов питания с требуемым комплексом показателей пищевой ценности / Н.Н. Липатов, И.А. Рогов // Известия вузов. Пищевая технология. – 1987. – № 2. – С. 9–15.
Липатов, Н.Н. Принципы и методы проектирования рецептур пищевых продуктов балансирующих рационы питания / Н.Н. Липатов // Известия вузов. Пищевая технология. – 1990. – № 6. – С. 5–11.
Потороко, И.Ю. Антиоксидантные свойства функциональных пищевых ингредиентов, используемых при производстве хлебобулочных и молочных продуктов, их влияние на качество и сохраняемость продукции / И.Ю. Потороко, А.В. Паймулина, Д.Г. Ускова и др. // Вестник ВГУИТ. – 2017. – Т. 79, № 4. – С. 143–151. DOI:10.20914/2310-1202-2017-4-143-151
Тутельян, В.А. Научные основы здорового питания / В.А. Тутельян и др. – М.: Издательский дом «Панорама», 2010. – 816 с.
Тутельян, В.А. Питание – это рычаг, который управляет миром / В.А. Тутельян. – http://medbook.ru/news/5809.
Тутельян, В.А. Приоритеты государственной политики здорового питания населения России на федеральном и региональном уровнях / В.А. Тутельян. – http://pfcop.opita-nii.ru/articles/state_feed_prioritets.shtml.
Чернуха, И.М. Продукты здорового питания: анализ классификационных признаков и методологические основы классификации / И.М. Чернуха // Все о мясе. – 2009. – № 1. – С. 24–28.
Шаззо, Р.И. Функциональные продукты питания / Р.И. Шаззо, Г.И. Касьянов. – М.: Колос, 2010. – 248 с.
Экспертиза специализированных пищевых продуктов. Качество и безопасность / Л.А. Маюрникова и др.; под общ. ред. В.М. Позняковского. – СПб.: ГИОРД, 2016. – 448 с.
Bermúdez-Soto, M.-J. Stability of polyphenols in chokeberry (Aronia melanocarpa) subjected to in vitro gastric and pancreatic digestion / M.-J. Bermúdez-Soto, F.-A. Tomás-Barberán, M.-T. García-Conesa // Food Chemistry. – 2007. – Vol. 102 (3). – P. 865–874.
Bouayed, J. Bioaccessible and dialysable polyphenols in selected apple varieties following in vitro digestionvs. their native patterns / J. Bouayed, H. Deußer, L. Hoffmann, T. Bohn // Food Chemistry. – 2012. – Vol. 131 (4). – P. 1466–1472.
Carbonell-Capella, J.M. Analytical methods for determining bioavailability and bioaccessibility of bioactive compounds from fruits and vegetables: A review / J.M. Carbonell-Capella, M. Buniowska, F.J. Barba, M.J. Esteve, A. Frígola // Comprehensive Re-views in Food Science and Food Safety. – 2014. – Vol. 13 (2). – P. 155–171.
David Julian, McClements. Enhancing nutraceutical bioavailability through food matrix design // Current Opinion in Food Science. – August 2015. – Vol. 4. – P. 1–6.
Hur, S.J. In vitro human digestion models for food applications / S.J. Hur, B.O. Lim, E.A. Decker, D.J. McClements // Food Chemistry. – 2011. – Vol. 125 (1). – P. 1–12.
McClements, D.J. Recent develop-ments in encapsulation and release of functional food ingredients: delivery by design / D.J. McClements // Current Opinion in Food Science. – 2018. – Vol. 23. – P. 80–84.
McClements, D.J. Advances in fabri-cation of emulsions with enhanced functionali-ty using structural design principles / D.J. McClements // Current Opinion in Colloid & Interface Science. – 2012. – Vol. 17. – P. 235–245.
McClements, D.J. Excipient foods: de-signing food matrices that improve the oral bioavailability of pharmaceuticals and nutraceuticals / D.J. McClements, H. Xiao // Food Funct. – 2014. – Vol. 5. – P. 1320–1333.
Sonochemical Micronization of Taxifolin Aimed at Improving Its Bioavailability in Drinks for Athletes / I.Yu. Potoroko, I.V. Kali-nina, N.V. Naumenko et al. // Человек. Спорт. Медицина. – 2018. – Т. 18, № 3. – С. 90–100. DOI: 10.14529/hsm180309
Tagliazucchi, D. In vitro bio-acces-sibility and antioxidant activity of grape polyphenols / D. Tagliazucchi, E. Verzelloni, D. Bertolini, A. Conte // Food Chemistry. – 2010. – Vol. 120 (2). – P. 599–606.
Yada, R.Y. et al. Engineered nanoscale food ingredients: evaluation of current knowledge on material characteristics relevant to uptake from the gastrointestinal tract / R.Y. Yada, N. Buck, R. Canady et al. // Comprehensive Reviews in Food Science and Food Safety. – 2014. – Vol. 13. – P. 730–744.
